Distrito Santa Isabel Vacations & Trips from $923

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Top destinations in Distrito Santa Isabel

A tropical island with a beach, clear turquoise waters, and lush greenery.

The Latest Distrito Santa Isabel Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Riu Plaza Panama

Bella Vista

$923

per person

Oct 1 - Oct 8

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

9/10 Wonderful! (5,763 reviews)

RIu hotel is excellent, they have great rooms, the location is good, breakfast was very good. My only complain and reason for not getting full excellent rating is that the tv set was old and the images ere blurry.

Reviewed on Aug 13, 2026

Megapolis Hotel Panamá

San Francisco

$1,039

per person

Oct 1 - Oct 8

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

8.4/10 Very Good! (1,628 reviews)

Fantastic hotel great price. Has its own mall. Everything within walking distance. All employees spoke fantastic English. Nice tapas as well. Shame the pool was undergoing some renovations but these things happen. Would highly recommend

Reviewed on Aug 13, 2026

Central Hotel Panama Casco Viejo

Casco Viejo

$994

per person

Oct 1 - Oct 8

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

9.2/10 Wonderful! (1,010 reviews)

Nice hotel. Great location. Good breakfast. Our only complaint is about noise. The hotel has live music in the atrium from early in the morning until about 10 pm. Our room, along with many others, had windows facing into the atrium, and the noise from the music, and sometimes large tour groups at breakfast, may disturb your sleep.

Reviewed on Aug 10, 2026

Hyatt Regency Panama City

Bella Vista

$1,056

per person

Oct 1 - Oct 8

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

9.6/10 Exceptional! (398 reviews)

The hotel was clean and everyone very helpful. The restaurant food is delicious and priced well.

Reviewed on Aug 13, 2026

Riande Aeropuerto Hotel & Casino

$985

per person

Oct 1 - Oct 8

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

8.4/10 Very Good! (1,814 reviews)

Needs Kleenex in bathroom

Reviewed on Aug 13, 2026

Find the Best Distrito Santa Isabel Vacation Packages

Distrito Santa Isabel Essential Information

Language	Spanish
Currency	Panamanian balboas
Local Welcome	¡Hola!
Local Goodbye	Adiós

Distrito Santa Isabel Hotel Deals

Caribbean Haven Of Nature 'Preci Beach'

Nombre de Dios Colon

10/10 Exceptional! (31 reviews)

Beautiful

"This place is special. The inside of the house could use a deep cleaning. But the outdoor area and beach area are incredible. We explored tide pools and snorkeled open areas and crevices all week long. Our one negative experience was fishing with some young men from the nearby town; they did not ..."

Reviewed on Mar 17, 2025

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BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

Santa Isabel Colon

10/10 Exceptional! (31 reviews)

"This was an incredible stay with so many lovely preparation of meals from Lucy and Jose. They were helpful and so thoughtful. We rested, relaxed, and spent leisurely days being together as a family. If only this happened more often! What a great trip. I am sad it ended so soon. Thank you to a wonderful ..."

Reviewed on Jan 1, 2026

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B&B Lodgings

C. Tercera El Valle de Cerro Azul 24 de Diciembre Panamá Province

Fully refundableReserve now, pay when you stay

$49 nightly

$54 total

Aug 15 - Aug 16

Total with taxes and fees

See all 155 properties in Distrito Santa Isabel

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.